Things get too close for comfort when Addison, Pete and Sam must come together on a complicated case involving a dad-to-be who comes down with tuberculosis and threatens the future of his new family. Meanwhile, with Violet still gone on her Costa Rican escape, Sheldon takes over helping one of her patients, Natasha, to get over her crippling fear of flying, and Naomi finds herself in a bit of a love triangle of her own.
Naomi, Addison and Pete try to save a premature baby. Cooper thinks Charlotte's new boyfriend is abusing pills.
Sam has Violet help plan Maya's wedding, as Naomi becomes more distant and refuses to help. Meanwhile, tensions arise between Addison and Sam as they treat a suicidal patient, and Cooper and Pete work together to treat a girl with a mysterious bite mark.
Addison and Cooper lend advice to a couple who must make a difficult choice as to which daughter to save with their newborn's core blood. Meanwhile, Sam learns that Dink is going to marry Maya, and the gang plans an intervention for Naomi.
Maya makes an announcement that shocks Sam and Naomi, and Naomi's response leaves Sam to pick up the pieces. Meanwhile, Pete's patient begins using a bionic arm.
Mark follows Addison to Oceanside hoping she will help him with his pregnant daughter. Meanwhile, Dell and Naomi have problems raising their children in the same house; and Violet and Cooper disagree on the course of treatment for a patient, resulting in a large argument.
After Dell's house is involved in a terrible explosion, it results in Betsey and Heather in the hospital, and everyone trying their best to save their lives. Meanwhile, the tension between Addison and The Captain rises even higher after her mother, Bizzy, shows up with a shocking family secret.
After Addison performs a complex in utero surgery, it finally gives a common ground between her and her father. Meanwhile, Naomi and Sam have to deal with their own family crisis when they uncover the fact that their daughter is growing up way too fast, and Violet does the unthinkable.
Addison is thrown by the arrival of her father to Los Angeles. Cooper is arrested when he refuses to cooperate in a case involving a patient. Pete fights to keep a terminally ill patient alive long enough for him to meet his daughter
Addison and Sam go for a hike in Malibu, they come across an expecting couple trapped in their car after an accident, they then perform urgent field care. Charlotte, Cooper and Violet treat a newlywed who, on his wedding night has taken too much Viagra. Pete and Sheldon go out to a bar together and end up falling for the same girl.
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